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Conclusion Our study revealed that Sert has a protective effect against cerebral I/R via multiple pathways, including inhibition of oxidative stress, increased polarisation of microglial cells to the anti-inflammatory M2 phenotype and hence, suppression of inflammation

Cornish S, Mehl-Madrona L

Without selenium, GPx cannot functionand without GPx, glutathione cannot effectively neutralize dangerous peroxides that damage lipids, proteins, and DNA

However, when these results were contrasted with the CCl 4 -induced liver failure group, no noteworthy changes were found in the levels of tissue TNF- (F 2,15 = 0.8731) and IL-1 (F 2,15 = 0.1304) in the rats treated with CS or Fe 3 O 4